Chloride → Methyl 3-(3-(4-methyl-3-(6-methylimidazo[1,2-a]pyridine-3-carboxamido)phenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate

HRID 88082Notes

Reaction equation

HRID 88082 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([cH:7]1)[c:8]([C:11](=[O:12])[OH:13])[cH:9][n:10]2.[CH3:51][N:52]([CH3:53])[CH:54]=[O:55].[Cl-:20].[Cl:14][C:15]([C:16]([Cl:17])=[O:18])=[O:19].[Cl:42][CH2:43][Cl:44].[NH2:21][c:22]1[cH:23][c:24](-[c:29]2[n:30][o:31][c:32]([CH:34]3[CH2:35][N:36]([C:38](=[O:39])[O:40][CH3:41])[CH2:37]3)[n:33]2)[cH:25][cH:26][c:27]1[CH3:28].[cH:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]2[n:6]([cH:7]1)[c:8]([C:11](=[O:13])[NH:21][c:22]1[cH:23][c:24](-[c:29]3[n:30][o:31][c:32]([CH:34]4[CH2:35][N:36]([C:38](=[O:39])[O:40][CH3:41])[CH2:37]4)[n:33]3)[cH:25][cH:26][c:27]1[CH3:28])[cH:9][n:10]2

Participants

8

Reactant 7

HCID 312ChlorideHCID 1049PyridineHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 552681936-Methylimidazo[1,2-a]pyridine-3-carboxylic acidHCID 86677444Methyl 3-(3-(3-amino-4-methylphenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate

Product 1

HCID 71280978Methyl 3-(3-(4-methyl-3-(6-methylimidazo[1,2-a]pyridine-3-carboxamido)phenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate

Sources & evidence

ORD record
ord-2923a69e6a3a4d599764e786a3a80001
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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