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HRID881323

反应详情

EQUATION

反应方程式

HRID 881323 的结构方程式

REACTANTS

反应物

3
结构：Cc1ccc(S(=O)(=O)O)cc1
HCID6101

4-Methylbenzenesulfonic acid

C7H8O3S

结构：C1=COCCC1
HCID8080

3,4-Dihydro-2H-pyran

C5H8O

结构：O=C(CO)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1
HCID86623522

未命名化合物

PRODUCTS

生成物

1
结构：O=C(COC1CCCCO1)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1
HCID86623523

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

1-(4-((2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxyethanone (730 mg) was reacted with 17 mg para-toluenesulfonic acid and 245 μL of 3,4-dihydro-2H-pyran in ethyl acetate overnight to yield 1-(4-((2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-(tetrahydro-2H-pyran-2-yloxy)ethanone.