HRID882579

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

HCID7852

Propylamine

C3H9N

结构：CC(C)(C)OC(=O)N[C@@]1(C(=O)O)C[C@@H]1c1ccccc1

HCID7009512

未命名化合物

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

HCID9886157

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

PRODUCTS

生成物

结构：CCCNC(=O)[C@]1(N)C[C@@H]1c1ccccc1.O=C(O)C(F)(F)F

HCID71294530

未命名化合物

收率 85%

PROCEDURE

实验过程

The title compound was prepared by coupling commercially available (1S,2R)-1-[(tert-butoxycarbonyl)amino]-2-phenylcyclopropanecarboxylic acid with n-propylamine in the presence of O-(7-azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate (HATU) and subsequent Boc detachment with trifluoroacetic acid (yield: 85% of theory over both stages).