Ethanol → HCID 3753262, compound

HRID 885608Notes

Reaction equation

HRID 885608 reaction equation
[CH2:1]([OH:3])[CH3:2].[H-].[Na+].[C:6](=[S:8])=[S:7].[CH2:9](Br)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>CN(C)C=O>[CH2:1]([O:3][C:6]([S:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[S:7])[CH3:2]

Participants

6

Reactant 4

HCID 702EthanolHCID 6348Carbon DisulfideHCID 7498Benzyl BromideHCID 24758Sodium hydride

Product 1

HCID 3753262HCID 3753262, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

1 g of Ethanol was dissolved in 50 g of dimethylforamide, 0.44 g of sodium hydride (60% paraffin) was added thereto, and the mixture was stirred for 4 hours. 1.8 mL of carbon disulfide was gradually added thereto, and the mixture was stirred for 12 hours. 1.3 mL of benzylbromide was gradually added to the mixture and the resultant was stirred at room temperature for 12 hours. Then, the reaction was terminated by adding 1 mL of methanol thereto. Ice was added to the resultant, and the resultant was subjected to extraction using ethyl ether and dried using magnesium sulfate to prepare benzyl methoxydithiomate.

Workup

  1. stirringthe mixture was stirred for 12 hours
  2. stirringthe resultant was stirred at room temperature for 12 hours
  3. customThen, the reaction was terminated
  4. additionby adding 1 mL of methanol
  5. additionIce was added to the resultant
  6. extractionthe resultant was subjected to extraction
  7. customdried
  8. customto prepare benzyl methoxydithiomate

Sources & evidence

ORD record
ord-c285747bef624e06815cd8dab9ef74b5
Source dataset
uspto-grants-2012_08
Patent number
US08242204B2

Reaction notes

Loading…