Acetic Acid → HCID 86650351, compound

HRID 885782Notes

Reaction equation

HRID 885782 reaction equation
Br[CH2:2][C:3]([O:11][CH3:12])=[CH:4][C:5](=[O:10])[C:6]([F:9])([F:8])[F:7].[C:13]([O-:16])(=[O:15])[CH3:14].[K+].C(O)(=O)C>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C(#N)C>[C:13]([O:16][CH2:2][C:3]([O:11][CH3:12])=[CH:4][C:5](=[O:10])[C:6]([F:9])([F:8])[F:7])(=[O:15])[CH3:14]

Participants

6

Reactant 3

HCID 176Acetic AcidHCID 517044Potassium AcetateHCID 51531135-bromo-1,1,1-trifluoro-4-methoxypent-3-en-2-one

Product 1

HCID 86650351HCID 86650351, compound

Reagents, catalysts & solvents 2

HCID 74236Tetrabutylammonium BromideCatalystHCID 6342AcetonitrileSolvent

Procedure

24.8 g (0.1 mol) of 5-bromo-1,1,1-trifluoro-4-methoxypent-3-en-2-one, 20 g of potassium acetate, 5 g of tetrabutylammonium bromide and 8 g of acetic acid were stirred in 300 ml of acetonitrile at 40° C. for 20 h. The precipitate was filtered off and the solvent was removed completely under reduced pressure.

Workup

  1. filtrationThe precipitate was filtered off
  2. customthe solvent was removed completely under reduced pressure

Sources & evidence

ORD record
ord-7f330ea03c0e44b48d5c4db88bd3b0d1
Source dataset
uspto-grants-2012_08
Patent number
US08242313B2

Reaction notes

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