Tetrahydrofuran → 2-Chloro-5,11-dihydro-11-ethyl-4-methyl-8-{2-(5-quinolinyloxy)ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Reaction equation
[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH3:71][CH2:72][O:73][C:74]([CH3:75])=[O:76].[Cl:13][c:14]1[cH:15][c:16]([CH3:35])[c:17]2[c:23]([n:24]1)[N:22]([CH2:25][CH3:26])[c:21]1[c:20]([cH:30][c:29]([CH2:31][CH2:32][OH:33])[cH:28][n:27]1)[C:19](=[O:34])[NH:18]2.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[OH:36][c:37]1[c:38]2[cH:39][cH:40][cH:41][n:42][c:43]2[cH:44][cH:45][cH:46]1.[c:47]1([P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62][cH:63][cH:64][cH:65]1>>[Cl:13][c:14]1[cH:15][c:16]([CH3:35])[c:17]2[c:23]([n:24]1)[N:22]([CH2:25][CH3:26])[c:21]1[c:20]([cH:30][c:29]([CH2:31][CH2:32][O:33][c:37]3[c:38]4[cH:39][cH:40][cH:41][n:42][c:43]4[cH:44][cH:45][cH:46]3)[cH:28][n:27]1)[C:19](=[O:34])[NH:18]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-406a3bcc18b648f98a52ce24eb9d71dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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