Hydrochloric Acid → 2-Chloronaphthalen-1-ol

HRID 893563Notes

Reaction equation

HRID 893563 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([OH:12])=[CH:4][CH:3]=1.OO.[ClH:15].[Na+].[Cl-]>C(O)C(N)(CO)CO.CO>[Cl:15][C:4]1[CH:3]=[CH:2][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]=1[OH:12]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 784Hydrogen PeroxideHCID 5234Sodium ChlorideHCID 117874-Chloro-1-naphthol

Product 1

HCID 118192-Chloronaphthalen-1-ol

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6503Tris(hydroxymethyl)aminomethaneSolvent2×

Procedure

Mix 1 volume of 3 mg 4-chloro-1-naphthol per ml. methanol with 5 volumes of a solution of 0.018% hydrogen peroxide in Tris buffered saline (20 mM Tris. HCl, 500 mM NaCl, pH 7.5). This mixture provides a complete chromogenic mixture for peroxidase. Filter paper can be impregnated with the mixture as above, and rehydrated prior to use as noted above.

Workup

  1. customThis mixture provides a complete chromogenic mixture for peroxidase
  2. filtrationFilter paper

Sources & evidence

ORD record
ord-e450cdd70f094da99a3cbb7d6dae3eed
Source dataset
uspto-grants-1992_06
Patent number
US05126276

Reaction notes

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