Chloride → HCID 20575476, compound

HRID 894365Notes

Reaction equation

HRID 894365 reaction equation
[CH:1]([O:4][CH2:5][C:6]1([C:12]([OH:14])=O)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)([CH3:3])[CH3:2].[Cl-].C[N:17](C)C=O>C1C=CC=CC=1>[CH:1]([O:4][CH2:5][C:6]1([C:12]([NH2:17])=[O:14])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 312ChlorideHCID 6228DimethylformamideHCID 205754601-[(1-Methylethoxy)methyl]cyclohexanecarboxylic acid

Product 1

HCID 20575476HCID 20575476, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

10 g of 1-isopropyloxymethyl 1-cyclohexyl carboxylic acid dissolved in 50 cm3 of benzene were heated under reflux for 5 hours together with 15 cm3 of thionyle chloride in the presence of 0.3 cm3 of dimethylformamide.

Workup

  1. temperaturewere heated

Sources & evidence

ORD record
ord-1b68ae80606648f2a37af7850cf3e7cb
Source dataset
uspto-grants-1981_08
Patent number
US04283420

Reaction notes

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