Potassium Carbonate → HCID 3837308, compound

HRID 894401Notes

Reaction equation

HRID 894401 reaction equation
[CH2:1]([N:3]([CH2:14][CH3:15])[C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1I)[CH3:2].[Cl:16][C:17]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:18]=1[NH2:19].C(=O)([O-])[O-].[K+].[K+]>C1(C)C(C)=CC=CC=1.[Cu]>[CH2:1]([N:3]([CH2:14][CH3:15])[C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:19][C:18]1[C:17]([Cl:16])=[CH:23][CH:22]=[CH:21][C:20]=1[Cl:24])[CH3:2]

Participants

6

Reactant 3

HCID 11430Potassium CarbonateHCID 118462,6-DichloroanilineHCID 10925153HCID 10925153, compound

Product 1

HCID 3837308HCID 3837308, compoundYield 81.8%

Reagents, catalysts & solvents 2

HCID 23978CopperCatalystHCID 7237O-XyleneSolvent

Procedure

A mixture of 6.0 g (0.019 mole) of N,N-diethyl(o-iodophenyl)acetamide, 3.38 g (0.021 mole) of 2,6-dichloroaniline, 2.93 g (0.021 mole) of anhydrous potassium carbonate, 1.0 g of copper powder and 1.0 g of cuprous iodide was reacted in 85 ml of xylene for 24 hours to obtain 5.46 g of a colorless needle having a melting point of 99° to 101° C. The yield was 81.4%.

Sources & evidence

ORD record
ord-d17d6d2c6fab4080a449a03a08cf7573
Source dataset
uspto-grants-1981_08
Patent number
US04283532

Reaction notes

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