Methyl benzenesulfonate → 1-(3-Chloro-4-fluorobenzyl)-5,6-dihydropyridin-2(1H)-one
Reaction equation
[CH3:17][Si:18]([N-:19][Si:20]([CH3:21])([CH3:22])[CH3:23])([CH3:24])[CH3:25].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:12])[CH2:8][CH2:9][CH2:10][CH2:11]2)[cH:13][cH:14][c:15]1[F:16].[Li+:26].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[c:27]1([S:28]([O:29][CH3:30])(=[O:31])=[O:32])[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:12])[CH:8]=[CH:9][CH2:10][CH2:11]2)[cH:13][cH:14][c:15]1[F:16]Participants
7
Sources & evidence
- ORD record
- ord-356b6cbe54964581be97ba186d173ddb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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