Hydrochloric Acid → 1-[6-Ethylsulfanyl-5-[(3-fluorophenyl)-methyl-carbamoyl]-4-methyl-pyridin-2-yl]-piperidine-4-carboxylic acid

HRID 89734Notes

Reaction equation

HRID 89734 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH2:6][CH2:7][N:8]([c:11]2[n:12][c:13]([S:29][CH2:30][CH3:31])[c:14]([C:18]([N:19]([CH3:20])[c:21]3[cH:22][c:23]([F:27])[cH:24][cH:25][cH:26]3)=[O:28])[c:15]([CH3:17])[cH:16]2)[CH2:9][CH2:10]1.[CH3:35][OH:36].[ClH:34].[Li+:33].[OH-:32]>>[O:2]=[C:3]([OH:4])[CH:5]1[CH2:6][CH2:7][N:8]([c:11]2[n:12][c:13]([S:29][CH2:30][CH3:31])[c:14]([C:18]([N:19]([CH3:20])[c:21]3[cH:22][c:23]([F:27])[cH:24][cH:25][cH:26]3)=[O:28])[c:15]([CH3:17])[cH:16]2)[CH2:9][CH2:10]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 961HydroxideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 67286850HCID 67286850, compound

Product 1

HCID 672868191-[6-Ethylsulfanyl-5-[(3-fluorophenyl)-methyl-carbamoyl]-4-methyl-pyridin-2-yl]-piperidine-4-carboxylic acid

Sources & evidence

ORD record
ord-b2938993325f4b9394ef7de76e6cecda
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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