Triethylamine → 2,2,4,4-Tetramethyl-7-trimethylsilylethynyl-chroman

HRID 89755Notes

Reaction equation

HRID 89755 reaction equation
[CH3:16][Si:17]([CH3:18])([CH3:19])[C:20]#[CH:21].[CH3:1][C:2]1([CH3:15])[O:3][c:4]2[cH:5][c:6]([Br:14])[cH:7][cH:8][c:9]2[C:10]([CH3:12])([CH3:13])[CH2:11]1.[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[I-:22].[Pd:30]([Cl:31])[Cl:32].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[CH3:1][C:2]1([CH3:15])[O:3][c:4]2[cH:5][c:6]([C:21]#[C:20][Si:17]([CH3:16])([CH3:18])[CH3:19])[cH:7][cH:8][c:9]2[C:10]([CH3:12])([CH3:13])[CH2:11]1

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 30165Iodide IonHCID 66111TrimethylsilylacetyleneHCID 18965395HCID 18965395, compound

Product 1

HCID 189663522,2,4,4-Tetramethyl-7-trimethylsilylethynyl-chroman

Sources & evidence

ORD record
ord-79354ae4b3db46f98cc2fde1f889e889
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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