反应详情

0.446 mL (5.44 mmol) of pyrrolidine and 1.366 g (9.882 mmol) of potassium carbonate are added to 20 mL of dimethylformamide. 1.038 g (4.941 mmol) of (4-bromomethyl-phenyl)-acetonitrile are added with stirring and the mixture is stirred for 12 hours at RT. The reaction mixture is evaporated down in the rotary evaporator and the residue is extracted with EtOAc and water. The organic phase is dried over magnesium sulphate and the solvent is removed using the rotary evaporator.

1. stirringthe mixture is stirred for 12 hours at RT
2. customThe reaction mixture is evaporated down in the rotary evaporator
3. extractionthe residue is extracted with EtOAc and water
4. dry with materialThe organic phase is dried over magnesium sulphate
5. customthe solvent is removed
6. customthe rotary evaporator