反应详情

温度

50 °C

To a solution of 3.69 g (30 mmol) of 3-amino benzyl alcohol in 20 ml DMSO was added 3.78 g (45 mmol) solid NaHCO3 and 2.91 ml (27 mmol) 1-bromobutane. The reaction was allowed to stir at 50° C. for 18 hours (overnight). Reaction was worked up by adding 250 ml water and product was extracted in ethyl acetate. Water was added, and the resultant mixture was extracted with EtOAc. The organic layer was washed with water and brine.

1. customReaction
2. extractionwas extracted in ethyl acetate
3. additionWater was added
4. extractionthe resultant mixture was extracted with EtOAc
5. washThe organic layer was washed with water and brine