Hydrochloric Acid → Acetic acid, 2-methylphenyl ester

HRID 904069Notes

Reaction equation

HRID 904069 reaction equation
[C:1]1([CH3:8])[C:6]([OH:7])=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9](Cl)(=[O:11])[CH3:10].Cl>>[C:9]([O:7][C:6]1[C:1]([CH3:8])=[CH:2][CH:3]=[CH:4][CH:5]=1)(=[O:11])[CH3:10]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 335O-CresolHCID 6367Acetyl chloride

Product 1

HCID 10778Acetic acid, 2-methylphenyl esterYield 95%

Procedure

Into a spherical flask provided with a condenser, a dropping funnel and containing 2 moles of o-cresol, 2.4 moles of acetyl chloride are introduced in 15 minutes. The bath is kept at 110° C. until the release of hydrochloric acid is completed, i.e. after about 3 hours, and then the o-cresol acetate as obtained is distilled under vacuum:

Workup

  1. customInto a spherical flask provided with a condenser, a dropping funnel
  2. additionare introduced in 15 minutes

Sources & evidence

ORD record
ord-5d24bdc1bbd34a8786535ebdd5d69f9c
Source dataset
uspto-grants-1980_10
Patent number
US04230624

Reaction notes

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