反应详情

31 g of H-Val-Val-OBut.HCl are subjected, analogously to Example 21 (B), to a condensation reaction with 37 g of Z-Glu(OBzl)-OH in dimethylformamide in the presence of 13.5 g of HOBt and 12.8 ml of N-ethylmorpholine, by means of 22 g of DCC. After working up analogously to this example, catalytic hydrogenation is carried out as described in Example 21 (C). The compound insoluble in ether is isolated and is a single substance according to thin layer chromatography. Yield 51 g.