Hydrochloric Acid → 5-Bromo-2-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]pyrimidine
Reaction equation
[Br:10][c:11]1[c:12]([O:13][CH:14]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[cH:20][c:21]([F:24])[cH:22][cH:23]1.[Br:1][c:2]1[cH:3][n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH3:34][CH:35]([OH:36])[CH3:37].[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[ClH:9]>>[Br:1][c:2]1[cH:3][n:4][c:5]([N:17]2[CH2:16][CH2:15][CH:14]([O:13][c:12]3[c:11]([Br:10])[cH:23][cH:22][c:21]([F:24])[cH:20]3)[CH2:19][CH2:18]2)[n:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-e87184aaac6b4f9cad1ee68c2704e89a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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