Potassium Carbonate → HCID 178513351, compound

HRID 910851Notes

Reaction equation

HRID 910851 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:3]=1[O:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1Cl.[ClH:19].[NH2:20][OH:21].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[NH2:1][C:2]1[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:3]=1[O:4][C:5]1[CH:12]=[CH:11][C:8]([C:9](=[NH:10])[NH:20][OH:21])=[CH:7][C:6]=1[Cl:19]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 443297Hydroxyamine hydrochlorideHCID 63092438HCID 63092438, compound

Product 1

HCID 178513351HCID 178513351, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The subtitle compound was prepared using the product from example 29 step i) (0.60 g) which was dissolved in ethanol (20 ml) and treated with hydroxylamine hydrochloride (0.30 g) followed by potassium carbonate (0.60 g). The mixture was heated at 90 C for 2 hours, cooled and the solid filtered off. The filtrate was concentrated under reduced pressure to give a red oil. Yield 0.94 g.

Workup

  1. temperatureThe mixture was heated at 90 C for 2 hours
  2. temperaturecooled
  3. filtrationthe solid filtered off
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. customto give a red oil

Sources & evidence

ORD record
ord-6812c1bdf12c4945bc338f8d35ef088a
Source dataset
uspto-grants-2011_09
Patent number
US08022248B2

Reaction notes

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