反应详情

温度

80 °C

About 0.75 g of 6-bromo-1,3-benzothiazol-2-amine (crude) is dissolved in about 15 mL DMF. About 0.5 mL of ethylisocyanate is added followed by about 0.9 mL triethylamine and the solution is heated to about 80° C. under good agitation. The solution is allowed to stir for about 4 hours then cooled to RT. The solvent is removed in vacuo and the solids are washed well with ether. The product is further purified by column chromatography.

1. temperaturethen cooled to RT
2. customThe solvent is removed in vacuo
3. washthe solids are washed well with ether
4. customThe product is further purified by column chromatography