Ammonium → N-[5-chloro-7-(3-methoxybut-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6,7-dimethoxyquinazolin-4-amine
Reaction equation
[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[Cl-:53].[Cl:16][c:17]1[c:18]([NH2:32])[c:19]2[c:20]([c:24]([C:26]#[C:27][CH:28]([CH3:29])[O:30][CH3:31])[cH:25]1)[O:21][CH2:22][O:23]2.[Cl:33][c:34]1[n:35][cH:36][n:37][c:38]2[cH:39][c:40]([O:46][CH3:47])[c:41]([O:44][CH3:45])[cH:42][c:43]12.[NH4+:54].[Na+:10].[O:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1.[O:48]=[CH:49][N:50]([CH3:51])[CH3:52]>>[Cl:16][c:17]1[c:18]([NH:32][c:34]2[n:35][cH:36][n:37][c:38]3[cH:39][c:40]([O:46][CH3:47])[c:41]([O:44][CH3:45])[cH:42][c:43]23)[c:19]2[c:20]([c:24]([C:26]#[C:27][CH:28]([CH3:29])[O:30][CH3:31])[cH:25]1)[O:21][CH2:22][O:23]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-df54807537ee474ca2f9e83a148b4526
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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