Hydrochloric Acid → Tromethamine hydrochloride

HRID 921475Notes

Reaction equation

HRID 921475 reaction equation
[CH2:1]([OH:8])[C:2]([NH2:7])([CH2:5][OH:6])[CH2:3][OH:4].[ClH:9]>O>[CH2:1]([OH:8])[C:2]([NH2:7])([CH2:5][OH:6])[CH2:3][OH:4].[ClH:9]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 6503Tris(hydroxymethyl)aminomethane

Product 1

HCID 93573Tromethamine hydrochloride

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

12.11 g of Trizma Base was dissolved in 80 ml DI H2O. The pH was adjusted to 8.5 with 1 N HCl solution, and the solution was adjusted to 100 ml with DI H2O.

Sources & evidence

ORD record
ord-d120f503ed574129bacf6d94e497fce1
Source dataset
uspto-grants-2016_03
Patent number
US09273123B2

Reaction notes

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