Chlorodiisopropylphosphine → HCID 178425660, Verbindung

HRID 925034Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 925034
[CH3:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]([NH:8][C:9]2[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:16])=[NH:7])=[CH:4][CH:3]=1.C([Li])CCC.Cl[P:25]([CH:29]([CH3:31])[CH3:30])[CH:26]([CH3:28])[CH3:27]>>[CH:26]([P:25]([CH:29]([CH3:31])[CH3:30])[N:7]=[C:6]([NH:8][C:9]1[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:16])[C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:18][CH:17]=1)([CH3:28])[CH3:27]

Komponenten

4

Edukt 3

HCID 538967ChlorodiisopropylphosphineHCID 178418339ButyllithiumHCID 178425630HCID 178425630, Verbindung

Produkt 1

HCID 178425660HCID 178425660, Verbindung

Versuchsvorschrift

Procedure as described for NP Amidine I using the following amounts: 1.19 g of 4-methyl-N1-(2,6-dimethylphenyl)benzamidine (Amidine III, 5.0 mmol), 2.50 mL of 2.0 M butyllithium (5.0 mmol), 0.80 mL chlorodiisopropylphosphine (5.0 mmol). After filtration to remove lithium chloride and removal of solvent, a yellow oil was isolated (1.76 g).

Aufarbeitung

  1. filtrationAfter filtration
  2. customto remove
  3. customlithium chloride and removal of solvent
  4. customa yellow oil was isolated (1.76 g)

Quellen und Nachweise

ORD-Eintrag
ord-7e05587c55fe4a859af7cc6655129a71
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09283555B2

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