Ammonium → Methyl 1-[(2'-t-butoxycarbonylbiphenyl-4-yl)methyl]-2-butyl-4-(1-hydroxy-2,2-dimethylpropyl)imidazole-5-carboxylate
Reaction equation
[Br-:1].[C:2]([CH3:3])([CH3:4])([CH3:5])[Mg+:6].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[c:14]1[c:15](-[c:20]2[cH:21][cH:22][c:23]([CH2:26][n:27]3[c:28]([CH2:38][CH2:39][CH2:40][CH3:41])[n:29][c:30]([CH:36]=[O:37])[c:31]3[C:32](=[O:33])[O:34][CH3:35])[cH:24][cH:25]2)[cH:16][cH:17][cH:18][cH:19]1.[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl-:53].[NH4+:54].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[C:2]([CH3:3])([CH3:4])([CH3:5])[CH:36]([c:30]1[n:29][c:28]([CH2:38][CH2:39][CH2:40][CH3:41])[n:27]([CH2:26][c:23]2[cH:22][cH:21][c:20](-[c:15]3[c:14]([C:12]([O:11][C:7]([CH3:8])([CH3:9])[CH3:10])=[O:13])[cH:19][cH:18][cH:17][cH:16]3)[cH:25][cH:24]2)[c:31]1[C:32](=[O:33])[O:34][CH3:35])[OH:37]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-2f6dbf17701c428ca8a6cb130218b3ed
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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