Dichloromethane → Benzyl 4-Hydroxy-1-piperidinecarboxylate

HRID 932951Notes

Reaction equation

HRID 932951 reaction equation
[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[O:22][C:23](=[O:24])[Cl:25].[CH3:8][CH2:9][N:10]([CH2:11][CH3:12])[CH2:13][CH3:14].[Cl:26][CH2:27][Cl:28].[NH:1]1[CH2:2][CH2:3][CH:4]([OH:7])[CH2:5][CH2:6]1>>[N:1]1([C:23]([O:22][CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)=[O:24])[CH2:2][CH2:3][CH:4]([OH:7])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 79341Piperidin-4-ol

Product 1

HCID 2794620Benzyl 4-Hydroxy-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-31b05fbc8e3b476694e8a9ba67eb94a4
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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