Acetic Acid → 7-Bromobenzo[b]thiophen-2-amine

HRID 932971Notes

Reaction equation

HRID 932971 reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([C:11]([OH:12])=[O:13])[s:9][c:10]12.[CH3:42][C:43](=[O:44])[OH:45].[CH:14]([N:17]([CH2:15][CH3:16])[CH:18]([CH3:19])[CH3:20])([CH3:21])[CH3:22].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50].[P:23]([N:24]=[N+:25]=[N-:26])(=[O:27])([O:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[O:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([NH2:17])[s:9][c:10]12

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 123414Diphenylphosphoryl azideHCID 179795837-Bromo-1-benzothiophene-2-carboxylic acid

Product 1

HCID 121122087-Bromobenzo[b]thiophen-2-amine

Sources & evidence

ORD record
ord-badc4ebc97c845879114c09eda105faf
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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