Tetrahydrofuran → N1,N1-Dimethyl-3-phenyl-1,2-propanediamine

HRID 933153Notes

Reaction equation

HRID 933153 reaction equation
[Al+3:2].[CH3:21][CH2:22][O:23][C:24](=[O:25])[CH3:26].[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[NH2:7][CH:8]([C:9](=[O:10])[N:11]([CH3:12])[CH3:13])[CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[NH2:7][CH:8]([CH2:9][N:11]([CH3:12])[CH3:13])[CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1

Participants

7

Reactant 6

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 126537772-amino-N,N-dimethyl-3-phenylpropanamide

Product 1

HCID 11769112N1,N1-Dimethyl-3-phenyl-1,2-propanediamine

Sources & evidence

ORD record
ord-bfca3aece7ca4891b8b11259c5b9e0bd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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