Hydrochloric Acid → 4-Tert-butyl-2-[5-(2-hydroxymethylphenylthiomethyl)benzofuran-2-yl]thiazole
Reaction equation
[Al+3:31].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7](-[c:10]2[o:11][c:12]3[c:13]([cH:14]2)[cH:15][c:16]([CH2:19][S:20][c:21]2[c:22]([C:27](=[O:28])[OH:29])[cH:23][cH:24][cH:25][cH:26]2)[cH:17][cH:18]3)[s:8][cH:9]1.[ClH:36].[H-:30].[H-:33].[H-:34].[H-:35].[Li+:32].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7](-[c:10]2[o:11][c:12]3[c:13]([cH:14]2)[cH:15][c:16]([CH2:19][S:20][c:21]2[c:22]([CH2:27][OH:28])[cH:23][cH:24][cH:25][cH:26]2)[cH:17][cH:18]3)[s:8][cH:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-018666f010c34f5a85ee4d8eb14c062d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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