Hydrochloric Acid → 1-(5-Chloroindol-2-ylsulphonyl)-4-[6-(4-pyridyl)nicotinoyl]piperazine

HRID 935489Notes

Reaction equation

HRID 935489 reaction equation
[CH3:36][N:37]([CH3:38])[CH2:39][CH2:40][CH2:41][N:42]=[C:43]=[N:44][CH2:45][CH3:46].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cl:16][c:17]1[cH:18][c:19]2[cH:20][c:21]([S:26](=[O:27])(=[O:28])[N:29]3[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]3)[nH:22][c:23]2[cH:24][cH:25]1.[ClH:35].[n:1]1[cH:2][cH:3][c:4](-[c:7]2[n:8][cH:9][c:10]([C:11](=[O:12])[OH:13])[cH:14][cH:15]2)[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4](-[c:7]2[n:8][cH:9][c:10]([C:11](=[O:13])[N:32]3[CH2:31][CH2:30][N:29]([S:26]([c:21]4[cH:20][c:19]5[cH:18][c:17]([Cl:16])[cH:25][cH:24][c:23]5[nH:22]4)(=[O:27])=[O:28])[CH2:34][CH2:33]3)[cH:14][cH:15]2)[cH:5][cH:6]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 22709453[2,4'-Bipyridine]-5-carboxylic acidHCID 227105715-chloro-2-(piperazine-1-sulfonyl)-1H-indole

Product 1

HCID 98913881-(5-Chloroindol-2-ylsulphonyl)-4-[6-(4-pyridyl)nicotinoyl]piperazine

Sources & evidence

ORD record
ord-351c3fd8905740e6885e60f002f51327
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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