Chloride → N-methoxy-N-methyl-1-phenylbicyclo[2.2.2]octane-4-carboxamide

HRID 935693Notes

Reaction equation

HRID 935693 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:21][NH:22][O:23][CH3:24].[CH:26]([Mg+:27])([CH3:28])[CH3:29].[Cl-:25].[ClH:20].[c:1]1([C:7]23[CH2:8][CH2:9][C:10]([C:15](=[O:16])[O:17][CH2:18][CH3:19])([CH2:11][CH2:12]2)[CH2:13][CH2:14]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]23[CH2:8][CH2:9][C:10]([C:15](=[O:16])[N:22]([CH3:21])[O:23][CH3:24])([CH2:11][CH2:12]2)[CH2:13][CH2:14]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 14232N,O-DimethylhydroxylamineHCID 21627803Ethyl 4-phenylbicyclo[2.2.2]octane-1-carboxylateHCID 178461726HCID 178461726, compound

Product 1

HCID 59379799N-methoxy-N-methyl-1-phenylbicyclo[2.2.2]octane-4-carboxamide

Sources & evidence

ORD record
ord-6e17cce3f51e4ab899e60002f7eecf1e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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