Formic Acid → 4-(3,5-Dichloro-pyridin-4-ylmethyl)-7-methoxy-1H-phthalazin-2-carbaldehyde

HRID 93653Notes

Reaction equation

HRID 93653 reaction equation
[C:39]([c:40]1[nH:41][cH:42][cH:43][n:44]1)([c:45]1[nH:46][cH:47][cH:48][n:49]1)=[O:50].[C:6]([n:7]1[cH:8][cH:9][n:10][cH:11]1)([n:12]1[cH:13][cH:14][n:15][cH:16]1)=[O:17].[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH:1](=[O:2])[OH:3].[CH:51]([OH:52])=[O:53].[Cl:18][c:19]1[cH:20][n:21][cH:22][c:23]([Cl:38])[c:24]1[CH2:25][C:26]1=[N:27][NH:28][CH2:29][c:30]2[cH:31][c:32]([O:36][CH3:37])[cH:33][cH:34][c:35]21.[N:4]#[N:5]>>[CH:1](=[O:3])[N:28]1[N:27]=[C:26]([CH2:25][c:24]2[c:19]([Cl:18])[cH:20][n:21][cH:22][c:23]2[Cl:38])[c:35]2[c:30]([cH:31][c:32]([O:36][CH3:37])[cH:33][cH:34]2)[CH2:29]1

Participants

7

Reactant 6

HCID 284Formic Acid2×HCID 947NitrogenHCID 8028TetrahydrofuranHCID 682631,1'-CarbonyldiimidazoleHCID 5250894Bis-(1H-imidazol-2-YL)-methanoneHCID 9797215Phthalazine, 4-[(3,5-dichloro-4-pyridinyl)methyl]-1,2-dihydro-7-methoxy-

Product 1

HCID 183816464-(3,5-Dichloro-pyridin-4-ylmethyl)-7-methoxy-1H-phthalazin-2-carbaldehyde

Sources & evidence

ORD record
ord-f4f4652b63854a73a00cb948d7a1618a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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