HRID936605

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID8471

Triethylamine

C6H15N

HCID13387

N-Methyl-2-pyrrolidone

C5H9NO

HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

HCID581866

2-Amino-4-chloropyridine

C5H5ClN2

结构：O=c1c(-c2ccc(O)c(F)c2)cnc(Nc2ccc(F)cc2)n1Cc1ccccc1

HCID59218362

未命名化合物

PRODUCTS

生成物

结构：Nc1cc(Oc2ccc(-c3cnc(Nc4ccc(F)cc4)n(Cc4ccccc4)c3=O)cc2F)ccn1

HCID59218371

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c486e8aede3f4ff1a101ca35cf53e394
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([NH:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[n:10][cH:11][c:12](-[c:15]2[cH:16][c:17]([F:22])[c:18]([OH:21])[cH:19][cH:20]2)[c:13]1=[O:14].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:46][N:47]1[CH2:48][CH2:49][CH2:50][C:51]1=[O:52].[CH3:53][N:54]([c:55]1[cH:56][cH:57][n:58][cH:59][cH:60]1)[CH3:61].[Cl:31][c:32]1[cH:33][c:34]([NH2:38])[n:35][cH:36][cH:37]1.[Cl:62][CH2:63][Cl:64]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([NH:23][c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[n:10][cH:11][c:12](-[c:15]2[cH:16][c:17]([F:22])[c:18]([O:21][c:32]3[cH:33][c:34]([NH2:38])[n:35][cH:36][cH:37]3)[cH:19][cH:20]2)[c:13]1=[O:14]