Ammonium → Tert-butyl 4-{2-[(3,5-bis-trifluoromethyl-benzyl)-(2-bromo-4,5-dimethoxy-benzyl)-amino]-pyrimidin-5-yloxy}-butyrate

HRID 936942Notes

Reaction equation

[Br:36][c:37]1[c:38]([CH2:47][Cl:48])[cH:39][c:40]([O:45][CH3:46])[c:41]([O:43][CH3:44])[cH:42]1.[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[Cl-:49].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][NH:7][c:8]2[n:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:12][n:13]2)[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33].[H-:34].[NH4+:50].[Na+:35].[O:51]=[CH:52][N:53]([CH3:54])[CH3:55]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([c:8]2[n:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:12][n:13]2)[CH2:47][c:38]2[c:37]([Br:36])[cH:42][c:41]([O:43][CH3:44])[c:40]([O:45][CH3:46])[cH:39]2)[cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1)([F:32])[F:33]