Hydrochloric Acid → Cyclopropanecarboxylic Acid 2-methyl-4-(2-methyl-4,5-dihydro-1-oxa-3,6-diaza-benzo[e]azulene-6-carbonyl)-benzylamide

HRID 936960Notes

Reaction equation

HRID 936960 reaction equation
[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH:1]1([C:4](=[O:5])[Cl:6])[CH2:2][CH2:3]1.[Cl:41][CH2:42][Cl:43].[ClH:7].[NH2:8][CH2:9][c:10]1[c:11]([CH3:33])[cH:12][c:13]([C:16](=[O:17])[N:18]2[c:19]3[c:20]([cH:29][cH:30][cH:31][cH:32]3)-[c:21]3[o:22][c:23]([CH3:28])[n:24][c:25]3[CH2:26][CH2:27]2)[cH:14][cH:15]1>>[CH:1]1([C:4](=[O:5])[NH:8][CH2:9][c:10]2[c:11]([CH3:33])[cH:12][c:13]([C:16](=[O:17])[N:18]3[c:19]4[c:20]([cH:29][cH:30][cH:31][cH:32]4)-[c:21]4[o:22][c:23]([CH3:28])[n:24][c:25]4[CH2:26][CH2:27]3)[cH:14][cH:15]2)[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 77637Cyclopropanecarbonyl chlorideHCID 57555237[4-(Aminomethyl)-3-methylphenyl]-(2-methyl-4,5-dihydro-[1,3]oxazolo[4,5-d][1]benzazepin-6-yl)methanone

Product 1

HCID 57555255Cyclopropanecarboxylic Acid 2-methyl-4-(2-methyl-4,5-dihydro-1-oxa-3,6-diaza-benzo[e]azulene-6-carbonyl)-benzylamide

Sources & evidence

ORD record
ord-7a736a5196af47d7855b1e3dcc15b64a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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