Tetrahydrofuran → 5-Bromo-1-(triisopropylsilyl)-1H-indole

HRID 939125Notes

Reaction equation

HRID 939125 reaction equation
[Br:11][c:12]1[cH:13][c:14]2[cH:15][cH:16][nH:17][c:18]2[cH:19][cH:20]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH:21]([CH3:22])([CH3:23])[Si:24]([CH:25]([CH3:26])[CH3:27])([CH:28]([CH3:29])[CH3:30])[Cl:31].[Li+:10]>>[Br:11][c:12]1[cH:13][c:14]2[cH:15][cH:16][n:17]([Si:24]([CH:21]([CH3:22])[CH3:23])([CH:25]([CH3:26])[CH3:27])[CH:28]([CH3:29])[CH3:30])[c:18]2[cH:19][cH:20]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 249055-BromoindoleHCID 28486Lithium ionHCID 139400Triisopropylsilyl chlorideHCID 3280088Npc316347

Product 1

HCID 27946525-Bromo-1-(triisopropylsilyl)-1H-indole

Sources & evidence

ORD record
ord-7323917a289a4c50a64e4620db06ae8c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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