Ammonium → 2-Acetyl-6-bromopyridine

HRID 939363Notes

Reaction equation

HRID 939363 reaction equation
[Br:1][c:2]1[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1.[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13].[CH3:14][C:15](=[O:16])[N:17]([CH3:18])[CH3:19].[CH3:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27].[Cl-:20].[NH4+:21].[OH2:28]>>[c:2]1([C:15]([CH3:14])=[O:16])[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 962WaterHCID 8058HexaneHCID 122742,6-DibromopyridineHCID 31374DimethylacetamideHCID 178418339Butyllithium

Product 1

HCID 112985782-Acetyl-6-bromopyridine

Sources & evidence

ORD record
ord-ec06c15287094155b481ca74c0c5ab6b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…