Diethyl Ether → 4,5-dihydro-3-(1-hydroxypropyl)-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Reaction equation
[CH2:2]([CH3:3])[I:4].[CH3:23][CH2:24][O:25][CH2:26][CH3:27].[CH3:5][N:6]1[CH2:7][c:8]2[n:9]([cH:18][n:19][c:20]2[CH:21]=[O:22])-[c:10]2[c:11]([cH:14][cH:15][cH:16][cH:17]2)[C:12]1=[O:13].[Mg:1].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH2:2]([CH3:3])[CH:21]([c:20]1[c:8]2[n:9]([cH:18][n:19]1)-[c:10]1[c:11]([cH:14][cH:15][cH:16][cH:17]1)[C:12](=[O:13])[N:6]([CH3:5])[CH2:7]2)[OH:22]Participants
6
Sources & evidence
- ORD record
- ord-473d3c096dd546d09771599aa9d8ba94
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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