Tetrahydrofuran → Trifluoro-methanesulfonic acid 3,5-dichloro-4-[cis-1-(4-fluoro-cyclohexyl)-2-oxo-pyrrolidin-3-ylmethyl]-phenyl ester

HRID 940347Notes

Reaction equation

[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:15][CH:16]([N-:17][CH:18]([CH3:19])[CH3:20])[CH3:21].[Cl:22][c:23]1[cH:24][c:25]([O:36][S:37](=[O:38])(=[O:39])[C:40]([F:41])([F:42])[F:43])[cH:26][c:27]([Cl:35])[c:28]1[CH2:29][O:30][S:31]([CH3:32])(=[O:33])=[O:34].[F:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]2[C:9](=[O:13])[CH2:10][CH2:11][CH2:12]2)[CH2:6][CH2:7]1.[Li+:14]>>[F:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]2[C:9](=[O:13])[CH:10]([CH2:29][c:28]3[c:23]([Cl:22])[cH:24][c:25]([O:36][S:37](=[O:38])(=[O:39])[C:40]([F:41])([F:42])[F:43])[cH:26][c:27]3[Cl:35])[CH2:11][CH2:12]2)[CH2:6][CH2:7]1