Hydrochloric Acid → 2-Acetyl-6-bromopyridine

HRID 941961Notes

Reaction equation

HRID 941961 reaction equation
[Br:12][c:13]1[n:14][c:15]([Br:19])[cH:16][cH:17][cH:18]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:21][N:22]([C:23]([CH3:24])=[O:25])[CH3:26].[CH3:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[ClH:20]>>[c:13]1([C:23]([CH3:24])=[O:25])[n:14][c:15]([Br:19])[cH:16][cH:17][cH:18]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 8058HexaneHCID 122742,6-DibromopyridineHCID 31374DimethylacetamideHCID 178418339Butyllithium

Product 1

HCID 112985782-Acetyl-6-bromopyridine

Sources & evidence

ORD record
ord-51c142c48f544c1f8bd86f0e4608f14c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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