Water → N-(Benzyloxycarbonyl)-5-fluorotryptamine

HRID 942045Notes

Reaction equation

HRID 942045 reaction equation
[CH2:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[O:28][C:29](=[O:30])[Cl:31].[CH3:14][N:15]1[CH2:16][CH2:17][O:18][CH2:19][CH2:20]1.[F:1][c:2]1[cH:3][cH:4][c:5]2[nH:6][cH:7][c:8]([CH2:9][CH2:10][NH2:11])[c:12]2[cH:13]1.[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH2:37]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[nH:6][cH:7][c:8]([CH2:9][CH2:10][NH:11][C:29]([O:28][CH2:21][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)=[O:30])[c:12]2[cH:13]1

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 10387Benzyl chloroformateHCID 1646825-Fluorotryptamine

Product 1

HCID 9948665N-(Benzyloxycarbonyl)-5-fluorotryptamine

Sources & evidence

ORD record
ord-0e333ef281e64ef0925d1eaf6415bd35
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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