Chloride → 6-[3-(2,4,6-trichlorobenzoyl)-6-fluorobenzyl)-2H-pyridazin-3-one

HRID 942225Notes

Reaction equation

HRID 942225 reaction equation
[Al+3:2].[C:35]([Cl:36])(=[O:37])[C:38]([Cl:39])=[O:40].[CH2:32]([Cl:33])[Cl:34].[CH2:41]([Cl:42])[Cl:43].[Cl-:1].[Cl-:3].[Cl-:4].[Cl:20][c:21]1[c:22]([C:23](=[O:24])[Cl:25])[c:26]([Cl:31])[cH:27][c:28]([Cl:30])[cH:29]1.[F:5][c:6]1[c:7]([CH2:8][c:9]2[cH:10][cH:11][c:12](=[O:15])[nH:13][n:14]2)[cH:16][cH:17][cH:18][cH:19]1.[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[F:5][c:6]1[c:7]([CH2:8][c:9]2[cH:10][cH:11][c:12](=[O:15])[nH:13][n:14]2)[cH:16][c:17]([C:23]([c:22]2[c:21]([Cl:20])[cH:29][c:28]([Cl:30])[cH:27][c:26]2[Cl:31])=[O:24])[cH:18][cH:19]1

Participants

8

Reactant 7

HCID 312Chloride3×HCID 6228DimethylformamideHCID 6344Dichloromethane2×HCID 65578Oxalyl chlorideHCID 104727Aluminum CationHCID 14805366-[(2-Fluorophenyl)methyl]-3(2H)-pyridazinoneHCID 27337032,4,6-Trichlorobenzoyl chloride

Product 1

HCID 543549036-[3-(2,4,6-trichlorobenzoyl)-6-fluorobenzyl)-2H-pyridazin-3-one

Sources & evidence

ORD record
ord-49b629600e254d779de1152bb41b1e19
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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