Hydrochloric Acid → Diethyl pyrimidine-2,4-dicarboxylate

HRID 942393Notes

Reaction equation

HRID 942393 reaction equation
[ClH:25].[N:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])=[O:7].[NH2:8][c:9]1[cH:10][c:11]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[n:12][c:13]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[n:14]1.[O:26]=[CH:27][N:28]([CH3:29])[CH3:30]>>[cH:9]1[cH:10][c:11]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[n:12][c:13]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[n:14]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 10906Tert-Butyl nitriteHCID 10857553Diethyl 6-aminopyrimidine-2,4-dicarboxylate

Product 1

HCID 66701935Diethyl pyrimidine-2,4-dicarboxylate

Sources & evidence

ORD record
ord-60c3845bd7b546a7a6e1deeabf55b8f3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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