Ammonium → 4-tert-butyl-N-{5-(3-methoxyphenoxy)-6-(2-pyridinylmethoxy)pyrimidin-4-yl}benzenesulfonamide

HRID 942731Notes

Reaction equation

HRID 942731 reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[c:15]1[cH:16][cH:17][c:18]([S:21](=[O:22])(=[O:23])[NH:24][c:25]2[n:26][cH:27][n:28][c:29]([Cl:40])[c:30]2[O:31][c:32]2[cH:33][c:34]([O:38][CH3:39])[cH:35][cH:36][cH:37]2)[cH:19][cH:20]1.[CH3:43][C:44]([N:45]([CH3:46])[CH3:47])=[O:48].[Cl-:41].[H-:9].[NH4+:42].[Na+:10].[n:1]1[c:2]([CH2:7][OH:8])[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([CH2:7][O:8][c:29]2[n:28][cH:27][n:26][c:25]([NH:24][S:21]([c:18]3[cH:17][cH:16][c:15]([C:11]([CH3:12])([CH3:13])[CH3:14])[cH:20][cH:19]3)(=[O:22])=[O:23])[c:30]2[O:31][c:32]2[cH:33][c:34]([O:38][CH3:39])[cH:35][cH:36][cH:37]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ionHCID 11474PiconolHCID 31374DimethylacetamideHCID 166653HydrideHCID 15391273p-t-butyl-N-[6-chloro-5-(m-methoxyphenoxy)-4-pyrimidinyl]benzenesulfonamide

Product 1

HCID 153912714-tert-butyl-N-{5-(3-methoxyphenoxy)-6-(2-pyridinylmethoxy)pyrimidin-4-yl}benzenesulfonamide

Sources & evidence

ORD record
ord-e5fe4f7f14a94710982b39729b22348e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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