Methanol → [6-Chloro-3-(2,2,2-trifluoro-acetyl)-indol-1-yl]-acetic acid
Reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:1][O:2][C:3]([CH2:4][n:5]1[cH:6][c:7]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][c:13]12)=[O:21].[CH3:30][OH:31].[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[Li+:23].[OH-:22].[OH2:24].[OH2:32]>>[O:2]=[C:3]([CH2:4][n:5]1[cH:6][c:7]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][c:13]12)[OH:21]Participants
8
Sources & evidence
- ORD record
- ord-4dbd5f523c2b4d90a82fc5f0befe0799
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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