Hydrochloric Acid → N-(4-chlorophenyl)-3-cyclohexyl-4-[4-(3-methyl-5-oxo-7H-imidazo[1,5-c]imidazol-6-yl)piperidin-1-yl]-4-oxobutanamide

HRID 943063Notes

Reaction equation

HRID 943063 reaction equation
[CH2:50]1[CH2:51][CH2:52][C:53]2=[N:58][CH2:57][CH2:56][CH2:55][N:54]2[CH2:59][CH2:60]1.[CH3:34][c:35]1[n:36][cH:37][c:38]2[n:39]1[C:40](=[O:49])[N:41]([CH:43]1[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]1)[CH2:42]2.[CH3:61][C:62]#[N:63].[CH3:64][CH2:65][N:66]([CH2:67][CH3:68])[CH2:69][CH3:70].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([CH2:10][CH:11]([C:12](=[O:13])[OH:14])[CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)=[O:21])[cH:6][cH:7]1.[ClH:32].[ClH:33].[OH:22][n:23]1[c:24]2[c:25]([cH:26][cH:27][cH:28][cH:29]2)[n:30][n:31]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([CH2:10][CH:11]([C:12](=[O:14])[N:46]2[CH2:45][CH2:44][CH:43]([N:41]3[C:40](=[O:49])[n:39]4[c:35]([CH3:34])[n:36][cH:37][c:38]4[CH2:42]3)[CH2:48][CH2:47]2)[CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)=[O:21])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 313Hydrochloric Acid2×HCID 6342AcetonitrileHCID 8471TriethylamineHCID 757711-HydroxybenzotriazoleHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 230840155-methyl-2-(4-piperidinyl)-1,2-dihydro-3H-imidazo[1,5-c]imidazol-3-oneHCID 178520702HCID 178520702, compound

Product 1

HCID 23138385N-(4-chlorophenyl)-3-cyclohexyl-4-[4-(3-methyl-5-oxo-7H-imidazo[1,5-c]imidazol-6-yl)piperidin-1-yl]-4-oxobutanamide

Sources & evidence

ORD record
ord-2c10dee4ac58417189e8c3b6358e3cfd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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