Isopropanol → 4-Chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine
Reaction equation
[CH3:10][N:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1.[CH:17]([N:18]([CH2:19][CH3:20])[CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[CH:26]([OH:27])([CH3:28])[CH3:29].[NH2:1][c:2]1[n:3][c:4]([Cl:9])[cH:5][c:6]([Cl:8])[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([N:14]2[CH2:13][CH2:12][N:11]([CH3:10])[CH2:16][CH2:15]2)[cH:5][c:6]([Cl:8])[n:7]1Participants
5
Sources & evidence
- ORD record
- ord-c46aa25ff15c4c41ae57741c789b7f4a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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