Dimethylformamide → 6-(6-aminopyrimidin-4-yl)oxy-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
Reaction equation
[CH2:40]([P:41]([OH:42])([OH:43])=[O:44])[CH2:45][CH3:46].[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:47][N:48]([c:49]1[cH:50][cH:51][n:52][cH:53][cH:54]1)[CH3:55].[F:22][C:23]([c:24]1[cH:25][c:26]([NH2:27])[cH:28][cH:29][cH:30]1)([F:31])[F:32].[NH2:1][c:2]1[cH:3][c:4]([O:8][c:9]2[cH:10][c:11]3[cH:12][cH:13][cH:14][c:15]([C:19](=[O:20])[OH:21])[c:16]3[cH:17][cH:18]2)[n:5][cH:6][n:7]1.[O:56]=[CH:57][N:58]([CH3:59])[CH3:60]>>[NH2:1][c:2]1[cH:3][c:4]([O:8][c:9]2[cH:10][c:11]3[cH:12][cH:13][cH:14][c:15]([C:19](=[O:21])[NH:27][c:26]4[cH:25][c:24]([C:23]([F:22])([F:31])[F:32])[cH:30][cH:29][cH:28]4)[c:16]3[cH:17][cH:18]2)[n:5][cH:6][n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9d9b467ed4784457bdbc31bfa5f13411
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…