Chloride → 5-phenyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

HRID 944025Notes

Reaction equation

HRID 944025 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[NH:8][C:9](=[O:11])[CH2:10]2.[CH3:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[CH3:36][CH2:37][OH:38].[CH3:43][CH2:44][O:45][CH2:46][CH3:47].[CH:39]([Cl:40])([Cl:41])[Cl:42].[Cl-:28].[Li+:27].[Na+:21].[Na+:22].[O-:23][C:24](=[O:25])[O-:26].[OH:12][B:13]([OH:14])[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[c:2]1(-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[cH:3][c:4]2[c:5]([n:6][cH:7]1)[NH:8][C:9](=[O:11])[CH2:10]2

Participants

11

Reactant 10

HCID 312ChlorideHCID 702EthanolHCID 923Sodium ion2×HCID 1140TolueneHCID 3283Diethyl EtherHCID 6212ChloroformHCID 19660Carbonate IonHCID 28486Lithium ionHCID 66827Phenylboronic AcidHCID 155040625-bromo-1H,2H,3H-pyrrolo(2,3-b)pyridin-2-one

Product 1

HCID 155040635-phenyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one

Sources & evidence

ORD record
ord-cdfd3479ca9b46c09e9239105d400014
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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