Hydrochloric Acid → 3-Methylsulfonyl-5-nitro-4-piperidinobenzoic acid

HRID 944898Notes

Reaction equation

HRID 944898 reaction equation
[CH2:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[CH3:24][CH2:25][O:26][C:27](=[O:28])[CH3:29].[Cl:1][c:2]1[c:3]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1[N+:11](=[O:12])[O-:13].[ClH:30].[OH2:31]>>[c:2]1([N:21]2[CH2:20][CH2:19][CH2:18][CH2:23][CH2:22]2)[c:3]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1[N+:11](=[O:12])[O-:13]

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 962WaterHCID 8082PiperidineHCID 8857Ethyl AcetateHCID 122745753-Methylsulfonyl-4-chloro-5-nitrobenzoic acid

Product 1

HCID 189454273-Methylsulfonyl-5-nitro-4-piperidinobenzoic acid

Sources & evidence

ORD record
ord-3e74791e98ac408986148673f6313d61
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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