Water → 4-(Piperazin-1-yl)-6-(trifluoromethyl)pyrimidine
Reaction equation
[CH2:12]1[CH2:13][NH:14][CH2:15][CH2:16][NH:17]1.[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29].[OH2:30]>>[c:2]1([N:14]2[CH2:13][CH2:12][NH:17][CH2:16][CH2:15]2)[n:3][cH:4][n:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-c0f2a7359bff43959b2e785653f74001
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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