Methylparaben → Tert-butyl 2-[(4-methoxycarbonylphenoxy)methyl]pyrrolidine-1-carboxylate

HRID 945662Notes

Reaction equation

HRID 945662 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:13][OH:14])[CH2:10][CH2:11][CH2:12]1.[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[O:45]=[C:46]([O:47][CH:48]([CH3:49])[CH3:50])[N:51]=[N:52][C:53]([O:54][CH:55]([CH3:56])[CH3:57])=[O:58].[OH:15][c:16]1[cH:17][cH:18][c:19]([C:20](=[O:21])[O:22][CH3:23])[cH:24][cH:25]1.[c:26]1([P:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42][cH:43][cH:44]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:13][O:14][c:16]2[cH:17][cH:18][c:19]([C:20](=[O:21])[O:22][CH3:23])[cH:24][cH:25]2)[CH2:10][CH2:11][CH2:12]1

Participants

6

Reactant 5

HCID 7456MethylparabenHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 550865tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 73241637Tert-butyl 2-[(4-methoxycarbonylphenoxy)methyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-89be38b3659546f1bb0948fffaaa21f3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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